首页 > 关于我们 > 背景

 

简介

  出生队列研究室是承担广州市重点科技项目“广州出生队列研究”的主要部门。项目拟对在广州市分娩的30 000名孕妇及其所生儿童进行长期的随访,并建立中国最大的正常人群亲子生物样品库,运用流行病学研究方法,探讨未来20年中,影响广州地区儿童和妇女健康的主要因素,测量社会、经济、文化、生物、环境等因素在影响这一弱势群体中的作用及其作用机理,从而验证一系列不良妊娠结局和儿童期疾病的病因假设,为提出改善儿童和妇女健康状况的干预措施提供科学依据,同时为改善医疗卫生服务,制定相关的医疗服务指南及政策提供依据。

发展历史

  2009年12月,夏慧敏主任邀请英国伯明翰大学KK Cheng教授来访,并讨论在我中心开展出生队列研究的可行性。随后,中心邀请多位国内外专家为出生队列研究设想提供意见与建议,同时夏慧敏主任也带领中心相关领域专家访问丹麦、挪威和英国著名的儿童出生队列研究。
2010年6月,夏慧敏主任宣布正式建立出生队列研究室,全面启动出生队列研究筹备工作,邱琇博士负责出生队列项目的总体组织管理工作。
2010年11月,“广州市出生队列生物样品库及关键技术平台的建立”获广州市市科学技术与信息化局重大科技专项立项。

研究计划

  建立亲子队列。招募广州市30000名孕妇及其所生婴儿,并随访儿童至成人。运用流行病学调查的方法,了解孕期母亲接触的环境、生物、社会因素对于胎儿生长发育的影响,并观察这些因素对于儿童成长的长期影响,从而验证一系列不良妊娠结局和儿童期疾病的病因假设。
建立中国最大的正常人群亲子生物样品库。生物库设计容量为30000对亲子随访18年约1000000人份生物标本。该生物库的建立将积累大样本量广州地区居民亲子生物样品,促进国内乃至国际的分子遗传学等基础研究,为生命医学研究发展提供基础支撑作用。
开发信息管理系统。开发具有本土知识产权的精确、合法和高效的流行病学-生物样品库信息管理系统,从而促进信息支撑技术在医疗卫生系统的应用。

研究团队

  出生队列研究室是本中心最具创新理念和最有活力的科室之一,它由出生队列研究管理委员会管理,并由国内专家组和国外专家组协助和支持开展出生队列研究,旗下包括流行病学组、专业技术组、生物样品库、核心技术组、信息组、宣传组、项目管理组、教学组和质控组。中心主任夏慧敏作为出生队列研究的核心领军人物,拥有3位博士后、7位博士和24位硕士,平均年龄不足32岁的研究团队。团队成员均毕业于国内著名高校或在国外留学多年,专业特长包括流行病学、生物统计学、分子生物学、医学遗传学、健康心理学等。整个出生队列研究的团队秉承“没有完美的个人,只有完美的团队”精神,集思广益、风雨同舟、相亲相爱、其乐融融。

诚挚欢迎您参与我们的研究

  我们的研究是填补国内空白的、对于母亲和儿童健康有着深远意义的研究,将对探明导致儿童乃至成人一些重要疾病的因素起到重大的作用。参与出生队列研究是完全自愿的。您的参与是十分重要的,您的贡献是光荣的!这将惠及我们自己、惠及更多的母亲和孩子!我们期待与您共同走过具有历史意义的20年!

交流方式

  电话联系:020-38367159

  电子邮件:bigzcs@sina.com

  联系地址:广州市金穗路9号,广州市妇女儿童医疗中心出生队列研究室

Brief introduction

  The Born in Guangzhou Cohort Study Department is the main department to undertake key project ‘The Born in Guangzhou Cohort Study’ in Guangzhou City. This project intends to invite 30 000 pregnant women and their children to have a long-term follow-up, to establish the largest biological parentage biobank in normal population in China, using epidemiological methods to explore the impact of the Guangzhou area in the next 20 years, find out the main factors of children and women's health, measuring the social, economic, cultural, biological, and environmental factors, and the mechanism of them, as well as to verify the cause of a series of adverse pregnancy outcomes and childhood diseases, improving child and women's health interventions to provide a scientific basis, and provide the basis for improving health services, the development of relevant medical service guidelines and policies.

Development History

December 2009, the CEO of Guangzhou Women and Children’s Medical Center Prof. Huimin Xia invited Professor KK Cheng, from the University of Birmingham to visit our medical center and discuss the feasibility of developing the birth cohort study in our center. Subsequently, we also invited many foreign experts to provide advice on how to establish the birth cohort study, and Prof. Huimin Xia also led the team members to visit Denmark, Norway and the famous British children birth cohort study.
June 2010, Prof. Huimin Xia formal announced the establishment of Born in Guangzhou Cohort Study Department, started preparations for the birth cohort study, Dr. Xiu Qiu is responsible for the overall organization and management of the birth cohort project.
November 2010, we obtained a project "the establishment of Biobank and key technology platforms of Born in Guangzhou Cohort Study" by the Guangzhou City Science and Technology and Information Bureau of major science and technology project.

Research plan

Our plan is to establish a cohort study in Guangzhou. Recruitment 30 000 pregnant women and their babies, and follow-up of children to adults. Using epidemiological methods to explore the impact of the Guangzhou, find out the main factors of children and women's health, measuring the social, economic, cultural, biological, and environmental factors, as well as to observe the long-term effects of these factors of the development of children, in order to verify a series of adverse pregnancy outcomes and childhood disease etiology assumptions.
We will also establish the largest biological parentage Biobank in China. The Biobank is designed to have 30,000 pairs of paternity and followed up for 18 years which about 1,000,000 biological specimens. The establishment of biobanks will accumulate a large sample volume of biological samples paternity residents in Guangzhou, to promote domestic and international basic research in molecular genetics, etc., also to provide basic support for the development of medical research.
The Born in Guangzhou Cohort Study will develop an information management systems as well. Develop accurate, legal and efficient local intellectual property Epidemiology - Biological Biobank information management system, to promote the information technology support in the application of medical and health system.

Research team

Born in Guangzhou Cohort Study Department is one of the most innovative and most dynamic departments of the center, which consists birth cohort study management committee, domestic and foreign expert group to assist and support the Born in Guangzhou Cohort Study (BIGCS). BIGCS Include epidemiological groups, professional technology groups, Biobank, information technology group, publicity groups, the project management group, teaching group and quality controls group. The CEO Prof. Huimin Xia as the core leader of BIGCS, there are 2 postdoctoral, 1 doctoral and 24 master, the average age of less than 32 years of research team. Team members have graduated from famous universities or studying abroad for many years, professional expertise include epidemiology, biostatistics, molecular biology, medical genetics, health psychology, etc. The entire birth cohort study team is brainstorming, enjoyable, and love each other, adhering to the "no perfect person, only perfect team" spirit.

Welcome to participate in our research

Our research is to fill the blank domestic for the mother and child health research, play a significant role to prove the importance of some diseases impact in children and adults. Participate in BIGCS is completely voluntary. Your participation is very important, your contribution is glorious! This will benefit ourselves, benefiting more mother and child! We look forward to working with you together through the historic 20 years!

Contact us

Telephone: 020-38367159/p>

Email: bigzcs@sina.com

Contact address: No. 9 Jinsui Road, The Born in Guangzhou Cohort Study Department, Guangzhou Women and Children’s Medical Center, Zhujiang Newtown, Guangzhou