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目标方向

  建立亲子队列。招募广州市30000孕妇及其所生婴儿,并随访儿童至成人。运用流行病学调查的方法,了解孕期母亲接触的环境、生物、社会因素对于胎儿生长发育的影响,并观察这些因素对于儿童成长的长期影响,从而验证一系列不良妊娠结局和儿童期疾病的病因假设。

  建立中国最大的正常人群亲子生物样品库。生物库设计容量为30000对亲子随访18年约1000000人份生物标本。该生物库的建立将积累大样本量广州地区居民亲子生物样品,促进国内乃至国际的分子遗传学等基础研究,为生命医学研究发展提供基础支撑作用。

  开发信息管理系统。开发具有本土知识产权的精确、合法和高效的流行病学-生物样品库信息管理系统,从而促进信息支撑技术在医疗卫生系统的应用。

Objectives

We are going to establish a paternity cohort study in Guangzhou, and target to recruit 30 000 pregnant women and their babies, and follow-up of children to adults. Using epidemiological methods to explore the impact of the Guangzhou, find out the main factors of children and women's health, measuring the social, economic, cultural, biological, and environmental factors, as well as to observe the long-term effects of these factors of the development of children, in order to verify a series of adverse pregnancy outcomes and childhood disease etiology assumptions.

We will also establish the largest biological parentage Biobank in China. The Biobank is designed to accommodate 30,000 pairs of paternity and followed up for 18 years which about 1,000,000 biological specimens. The establishment of biobanks will accumulate a large sample volume of biological samples paternity residents in Guangzhou, to promote domestic and international basic research in molecular genetics, etc., also to provide basic support for the development of medical research.

The Born in Guangzhou Cohort Study will develop an information management systems as well, which to develop accurate, legal and efficient local intellectual property Epidemiology - Biological Biobank information management system, to promote the information technology support in the application of medical and health system.